Tim Cunningham, Ph.D.
Associate Professor of Chemistry
– Principles of Chemistry I and II
– Communication in Chemistry
– Fermentation and Distillation Science
– Physical Chemistry: Thermodynamics
– Physical Chemistry: Quantum Mechanics
Learn more about Dr. Cunningham
Tim has been a member of the chemistry department since 2015.
Teaching, mentoring, and scientific communication, in addition to extensive experience with spectroscopic, protein purification, computational modelling and chromatographic methods. Electron spin resonance (ESR) spectroscopy.
B.S. in Chemistry, Mercyhurst College (now University)
Ph.D. in Chemistry, University of Pittsburgh
Lawless M.J., Ghosh S., Cunningham T.F., Shimshi A., Saxena S. (2017) On the use of the Cu2+-iminodiacetic acid complex for double histidine based distance measurements by pulsed ESR. Phys Chem Chem Phys. 19 (31) 20959-20967.
Lawless M.J., Shimshi A., Cunningham T.F., Kinde M.N., Tang P., Saxena S. (2017) Analysis of Nitroxide-Based Distance Measurements in Cell Extracts and in Cells by Pulsed ESR Spectroscopy, Chemphyschem. 18 (12), 1653-1660.
Cunningham, T.F., Pornsuwan, S., Horne, W., and Saxena, S. (2016) Rotameric preferences of a protein spin label at edge-strand β-sheet sites, Protein Sci. 5, 1049-1060.
Cunningham, T.F., Putterman, M. R., Desai, A., Horne, W., and Saxena, S. (2015) The double histidine Cu2+-binding motif – A highly rigid, site-specific spin probe for electron spin resonance distance measurements, Angew. Chem. Int. Ed. 54, 6330-6334.
Cunningham, T.F., Shannon, M. D., Putterman, M. R., Arachchige, R., Sengupta, I., Gao, M., Jaroniec, C.P., and Saxena, S. (2015) Cysteine Specific Cu2+ Chelating Tags used as Paramagnetic Probes in Double Electron Electron Resonance, J. Phys. Chem. B 119, 2839-2843.
Sengupta, I., Gao, M., Arachchige, R., Nadaud, P. S., Cunningham, T.F., Saxena, S., Schwieters, C., and
Jaroniec, C. P. (2014) Protein Structural Studies by Paramagnetic Solid-State NMR Spectroscopy Aided by a
Compact Cyclen-Type Cu(II) Binding Tag, J. Biomol. NMR. 61, 1-6.
Cunningham, T.F., McGoff, M., Sengupta, I., Jaroniec, C., Horne, W., and Saxena, S. (2012) Highresolution structure of a protein spin-label in a solvent-exposed β-sheet and comparison with DEER spectroscopy. Biochemistry 51, 6350–9.
Mamonov, A. B., Lettieri, S., Ding, Y., Sarver, J. L., Palli, R., Cunningham, T.F., Saxena, S., and Zuckerman, D. M. (2012) Tunable, mixed-resolution modeling using library-based Monte Carlo and graphics processing units. J. Chem. Theory Comput. 8 (8), 2921-2929.
Ruthstein, S., Stone, K., Cunningham, T.F., Ji, M., Cascio, M., and Saxena, S. (2010) Pulsed electron spin resonance resolves the coordination site of Cu2+ ions in α1-glycine receptor. Biophys. J. 99, 2497–2506.