Edward Hall

Associate Professor of Chemistry

halled@hanover.edu
812-866-7254

Edward Hall

Classes:

– Organic Chemistry I and II
– Medicinal Chemistry
– Fermentation and Distillation Science

Learn more about Dr. Hall

Eddie has been a member of the Hanover College chemistry department since 2015. He obtained his Ph.D. from Indiana University studying new classes of antibiotics and designing fluorescent molecules in aid in the study of bacterial growth and development. His interest in these areas has continued at Hanover with undergraduate students aiding in related projects each school year. He stays busy with his family of four in Hanover and enjoys attending as many on-campus events with his students as possible.

Specializations

organic chemistry, peptide synthesis, photocatalysis, organocatalysis, metal-organic frameworks, fermentation science, medicinal chemistry

Education

B.S. in Chemistry, Ball State University

Ph.D. in Organic Chemistry, Indiana University

Postdoctoral Researcher, Northwestern University

Publications

Hsu, Y.P.; Hall, E.; Booher, G.; Murphy, B.; Radkob, A.V.; Yablonowski, J.; Mulcahey, C.; Alvarez, L.; Cava, F.; Brun, Y.V.; Kuru, E.; VanNieuwenhze, M.S. “Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays.” Nature Chem. 2019, 11, 335-341.

Hsu, Y.P.; Rittichier, J.; Kuru, E.; Yablonowski, J.; Pasciak, E.; Tekkam, S.; Hall, E.; Murphy, B.; Lee, T. K.; Garner, E. C.; Huang, K. C.; Brun, Y. V.; VanNieuwenhze, M. S. “Full Color Palette of Fluorescent D-Amino Acids for in situ Labeling of Bacterial Cell Walls” Chem. Sci. 2017, 8, 6313-6321.

Hall, E.; Wang, M.; Redfern, L.; Scheidt, K. “Lewis Acid Activation of a Hydrogen Bond Donor Metal-Organic Framework for Catalysis” ACS Catal. 2016, 6, 3248-3252.

Liechti, G.; Kuru, E.; Rittichier, J.; Tekkam, S.; Hall, E.; Hsu, Y. P.; VanNieuenhze, M.; Brun, Y.; Maurelli, A. “Pathogenic Chlamydia lack a ‘classical’ sacculus but synthesis a narrow, midcell peptidoglycan ring, regulated by MreB, for cell division” PLoS Pathog. 2016, 12, 5, 1-30.

Kuru, E.; Tekkam, S.; Hall, E.; Brun, Y.; VanNieuwenhze, M. S. “Synthesis of Fluorescent D- Amino Acids and Their Use for Specific and Covalent Labeling of Bacterial Peptidoglycan Cell Walls In Situ,” Nature Protocols, 2015, 10, 33-52.

Liechti, G.; Kuru, E.; Hall, E.; Kalinda, A.; Brun, Y. V.; VanNieuwenhze, M. S.; Maurelli, A. “A new metabolic cell wall labeling method reveals peptidoglycan in Chlamydia trachomatis,” Nature, 2014, 506, 507-510.

Pilhofer, M.; Aistleitner, K.; Biboy, J.; Gray, J.; Kuru, E.; Hall, E.; Brun, Y.; VanNiuewenhze, M. S.; Vollmer, W.; Horn, M.; Jensen, G. “Discovery of chlamydial peptidoglycan reveals bacteria with murein sacculi but without FtsZ,” Nat Commun, 2013, 4, 2856, DOI: 10.1038/ncomms3856.

Kuru, E.; Hughes, H. V.; Brown, P. J. B.; Hall, E.; Tekkam, S.; Cava, F.; de Pedro, M. A.; Brun, Y. V.; VanNieuwenhze, M. S. “Direct Fluorescent Labeling of Newly Synthesized Peptidoglycan in Live Bacterial Cells,” Angew. Chem. Int. Ed. 2012, 51, 12519-12523.

Hall, E.; Kuru, E.; VanNieuwenhze, M. S. “Solid-Phase Synthesis of Lysobactin (Katanosin B): Insights into Structure and Function,” Org Lett. 2012, 14, 2730-2733.

Patents

Kuru, E.; Hall, E. A.; Brun, Y. V., VanNieuwenhze, M. S. “Molecular Rotor-Based D-Amino Acids as Tools for Imaging Peptidoglycan Biosynthesis,” United States Provisional Patent Application, filed August 6, 2020.

Kuru, E.; Hall, E. A.; VanNieuwenhze, M. S. “Compositions for Covalently Labeling Bacterial Cell Walls with Fluorophores and Methods of Use,” United States Provisional Patent Application, filed April 21, 2012.

Dr. Hall in the Classroom

professor eddie hall teaches organic chemistry in a lecture hall